Quantifying the Implementation and Cost of a Multisite Antibiotic Stewardship Intervention for Asymptomatic Bacteriuria

Abstract Objective: The intensity of an antibiotic stewardship intervention to achieve clinical impact is not known. We conducted a multisite dissemination project reduce treatment asymptomatic bacteriuria (ASB) and studied: (1) the association between implementation metrics outcomes (2) cost implementation. Design/Setting/Participants: A central site facilitated multimodality decrease unnecessary urine cultures in patients with ASB at 4 Veterans Affairs medical centers. Methods: consisted decision support aid algorithm interactive teaching cases that provided moment audit feedback on how manage ASB. Implementation included minutes spent delivery, number healthcare professionals reached, sessions delivered. Clinical days therapy (DOT), length (LOT), ordered per 1000 bed days. Personnel reported weekly time logs. Results: Minutes delivery were inversely correlated two outcomes, DOT ( R −0.3, P = .04) LOT .02). Number reached delivered –0.003, .98, −0.059, .69) or +0.073, .62, −0.102, .49). Physician champions average 3.8% effort intervention. was USD 22,299/year average. Conclusions: amount local teams desired use. Implementing this successful required minimal time.